glp-1 vs gip Comparison between RA and the GLP-1/GIP dual agonist Upcoming wave of hormone-based therapies

In crude analyses, GLP-1 receptor agonist use was associated with an increased incidence of suicidality compared with DPP-4 inhibitors (crude incidence rates 3.9 v 1.8 per 1000 person years, respectively

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We used version 2 of the Cochrane risk-of-bias tool for randomised trials to assess risk of bias for the primary outcome

Secondary outcomes were each of these events considered separately