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Emerging treatment mechanisms for depression: focus on glutamate and synaptic plasticity
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Inefficient energy metabolism affects insulin sensitivity and insulin-like growth factor function, impacting blood glucose regulation
Mechanistically, tirzepatide treatment led to activation of brain areas that are known to control appetite and feeding behavior in rodents [67], a finding that is consistent with another GLP-1 analogs (semaglutide) activity in the brain [68]
How Are GLP-1 Patches Supposed to Work
it primarily reduces hunger signals through central nervous system activity
