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Description
Diabetes Care (2022) 45(Supplement_1):S12543

Patients are excluded if they have certain medical conditions (including thyroid cancer or severe eating disorders), are pregnant or breastfeeding, experience hormonal changes during the program, use other weight-loss methods or medications not prescribed through Eden's provider network during the six-month term, or do not fully satisfy all of the requirements above

Key Takeaways Retatrutide activates GLP-1R, GIPR, and GCGR simultaneously, making it structurally distinct from both semaglutide (GLP-1 only) and tirzepatide (GLP-1 and GIP only)
While Semaglutide GLP-1 injections have been shown to have impressive weight loss results, its important to note that these injections are not meant as a quick-fix solution

To truly heal and live symptom-free with PCOS, you need to make intentional lifestyle changes that support your hormones every day

Rare heterozygous loss-of-function variants in the human GLP-1 receptor do not associate with cardiometabolic phenotypes
