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Traditional weight loss often occurs gradually, allowing the skin time to adjust
Any family history of thyroid cancer or pancreatitis

doi:10.1098/rsfs.2019.0092

Tirzepatide's dual GLP-1 and GIP receptor agonism makes it highly effective for weight lossclinical trials show average weight reduction of 2022% at the highest doses

The doses of liraglutide or semaglutide are different depending on whether the patient has DT2, is overweight (BMI 27kg/m2) with comorbidities or has obesity (with or without DT2)

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