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however, the apparent volume of distribution (V/F) of metformin following single oral doses of immediate-release metformin HCl tablets 850 mg averaged 654 358 L

Proper sterile technique becomes even more important with higher injection frequency

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Contraindications include a history of medullary thyroid carcinoma, multiple endocrine neoplasia syndrome type 2 (MEN 2), pancreatitis, significant gastroparesis, or gallbladder disease