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3.5 Risk of bias assessment The Cochrane Risk of Bias tool (RoB 2) was used to thoroughly assess the methodological quality of the 40 included RCTs

However, these benefits can vary widely between individuals, making patient selection critical

Lda-Rgo G, Studart-Bott P, Abbade P, Rabelo-Da-Ponte FD, Casqueiro JS, Sarmento S, et al

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Multiple doses of sitagliptin, a selective DPP-4 inhibitor, do not meaningfully alter pharmacokinetics and pharmacodynamics of warfarin

Figure 1 below depicts the incretin effect in a normal patient versus a diabetic patient
