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Less common side effects (may affect up to 1 in 100 people)

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Tirzepatide activates two hormone pathways that regulate appetite and metabolism, making it effective for reducing stubborn abdominal fat

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The molecule is classified as a triple receptor agonist because it interacts with three endocrine receptors involved in metabolic regulation: the glucagon-like peptide-1 receptor (GLP-1R), the glucose-dependent insulinotropic polypeptide receptor (GIPR), and the glucagon receptor (GCGR)

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That same year, the American Diabetes Association updated its guidelines to make GLP-1s a first-line therapy for type 2 diabetesfurther increasing demand

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Learn which supplements support GLP-1 weight loss

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