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Methods PIONEER REAL Switzerland was a 3444-week, multicentre, prospective, non-interventional, single-arm study of adults with T2D nave to injectable glucose-lowering medication who were initiated on oral semaglutide in routine clinical practice

After 1 year of follow-up, the mean weight loss from baseline with semaglutide 2.4 mg and tirzepatide was 14.6 and 17.2 kg, respectively, with percent weight loss of 14.1% and 16.5%

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Retatrutide is supplied as a lyophilised powder and must be reconstituted with bacteriostatic water before use in any laboratory protocol