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Zepbound will be added to its formulary starting October 1

Accessed June 22, 2007

Preservation of muscle and bone mass The adverse effects of weight reduction on muscle and bone massparticularly among individuals with insufficient physical activity or protein intake or at older ages [59,149]have highlighted the interrelated priorities to preserve muscle mass, muscle quality, bone mass, and physical function

While the body does produce natural GLP-1, this endogenous hormone is rapidly broken down by the enzyme dipeptidyl peptidase-4 (DPP-4) within minutes of secretion, making it unsuitable as a therapeutic agent without pharmaceutical modification

The breadth reflects Eli Lilly's strategy of establishing retatrutide not just as a weight-loss drug but as a cardiometabolic platform