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What are the most common side effects of GLP-1 therapy
27-34 PIONEER 1 PIONEER 1 compared the efficacy and safety of oral semaglutide as monotherapy with placebo in patients with T2DM managed by diet and exercise alone

Given these differences, selecting the right GLP-1RA should be based on individual patient needs, including glycemic targets, weight loss goals, tolerability, and preference for dosing frequency
GLP1 receptor agonists directly address this demand by enhancing insulin secretion, reducing glucagon release, and preventing postmeal glucose spikes

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