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The crude residue was purified by silica gel flash column chromatography ( n -heptane:EtOAc, 2:1) yielding 4-nitrophenyl (2-(pyridin-2-yldisulfaneyl)ethyl) carbonate (89%)

A retrospective longitudinal analysis of ambulatory care data with a median follow-up of 3.5 years showed that twice-daily exenatide use with or without insulin was associated with significantly fewer cardiovascular events than insulin treatment [101]

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Berger AL, Henricks AM, Lugo JM, Wright HR, Warrick CR, Sticht MA, et al

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