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Furthermore, targeted delivery of exendin-4 to the nucleus of the solitary tract (NTS) similarly diminished both operant responding for sucrose under a progressive ratio schedule and conditioned place preference for food rewards in rats (Richard et al., 2015)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 10.Stempniewicz N., Vassalotti J.A., Cuddeback J.K., et al

Researchers found that the safety profiles of both drugs were generally consistent with the GLP-1 receptor agonist class

The company sees the drug as a major driver in maintaining its lead in the fast-growing weight-loss market, amid competition with Novo Nordisk A/S (NVO).
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