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Improved blood sugar control is another key benefit, particularly for those with type 2 diabetes

Billon 2023 (ACS Chemical Biology) Preclinical in vivo, 15-28 days, C57BL/6J mice (n = 8-10 per group)

Hematology and biochemistry laboratory parameters were measured at screening and weeks 20, 52, 84, and 104

Continuing semaglutide treatment is still recommended as it will likely allow weight loss to resume over time

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Specifically, disruption of the blood-brain barrier (BBB) is a critical pathologic process of EBI and shows promise as a therapeutic target in ameliorating the detrimental effects of SAH ( Matrix metalloproteinase-9 (MMP-9), a member of zinc- and calcium-dependent proteolytic enzymes family,(Rosell and Lo, 2008) is widely distributed in multiple cell types such as neurons, astrocytes, microglia, and endothelial cells, across the central nervous system (CNS) (Ying et al., 2016)