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Synaptic and extrasynaptic NMDA receptors are controlled by different endogenous coagonists

The Saudi climate subjects shipments to ambient temperatures exceeding 45C (113F) during the summer, with tarmac temperatures at logistics hubs in Riyadh or Jeddah reaching even higher

mild nausea (10-15%)

Elevated cortisol promotes visceral fat storage, increases water retention, impairs muscle recovery, and can trigger emotional eating patterns that the medication only partially counteracts

Because the study was observational, it cannot establish a direct cause-and-effect relationship

Preclinical studies in animal models have suggested that some GLP-1 analogues may cross the blood-brain barrier, though the extent of this penetration in humans remains uncertain