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This finding may also explain the greater glucose-lowering effects of DPP-4 inhibitors in East Asian populations, where saturated fat intake is generally lower than in Western countries [20]

Gradual Dose Titration Weekly semaglutide injections started low and increased gradually to minimize nausea and digestive side effects while appetite control builds

73 Addressing this conflict between reduced appetite and increased protein need is a key element of a successful muscle-sparing strategy on GLP-1 therapy

Free Radic Biol Med 213:1935

Fisman EZ, Tenenbaum A

This is because discontinuing early can be viewed as non-adherence to the approved treatment plan