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Suspected pancreatitis requires immediate medical evaluation and permanent tirzepatide discontinuation

DOI: 10.1007/s40262-022-01130-5 | Dr Miguel Angel Rodriguez

Clinical trial results discussed in this article - STEP 1 (14.9% average body weight loss with semaglutide), SURMOUNT-1 (20.9% average body weight loss with tirzepatide), and SELECT (20% reduced risk of major cardiovascular events with FDA-approved Wegovy in a specific patient population) - relate to studied active ingredients and specific FDA-approved formulations in controlled trial populations and should not be interpreted as guaranteed outcomes for any individual patient or compounded formulation

We chose a fixed-effects model when heterogeneity was low

For users with a history of reactions, the before-and-after ice protocol provides the most comprehensive prevention
