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Amsterdam JD, Shults J, Rutherford N, Schwartz S
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In major studies, participants were not always required to do formal exercise
Because GLP-1 agents can reduce insulin requirements, patients may inadvertently lower their insulin dose too much
is supported by the NIHR Oxford Biomedical Research Centre
A) Activation of POMC neurons by GLP-1 and 5-HT, particularly through the 5-HT2C receptor, leads to the release of -MSH, an endogenous agonist for MC4R
