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Dual GIP and GLP-1 receptor agonist Tirzepatide improves Beta-cell function and insulin sensitivity in type 2 diabetes

doi: 10.1001/archinte.149.9.1942

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[25] In a groundbreaking study, researchers found that berberine treatment restored GLP-1 secretion in diet-induced obese mice, not only reversing the decline in GLP-1 levels but actually increasing them above baseline compared to healthy controls

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Whether differences in serotonin are preexisting prior to surgery in those who develop PBH, or solely develop in response to the altered intestinal anatomy postoperatively, is an interesting question for future studies