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Heartburn (a burning sensation in the chest) and acid regurgitation are common symptoms of acid reflux, which can be part of gastroesophageal reflux disease (GERD) when chronic

Increased stomach acid: Alcohol can also increase stomach acid, which may lead to heartburn-like symptoms, including a sore throat
The findings of the present study align with this pattern, as participants had higher anxiety and lower depressive symptoms, which may explain the similar trends observed in HAM-A and HAM-D scores

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Furthermore, systemic MOTS-c treatment can downregulate proinflammatory IFN- and IL-17A cytokine production in NOD pancreas tissues suggesting the noncell-autonomous regulation by MOTS-c 7
Other rarer causes of gastroparesis include diseases affecting the extrinsic neural control (such as Parkinsonism, amyloidosis, and paraneoplastic disease) or disorders that result in infiltration or degeneration of the muscle layer of the stomach (such as scleroderma)
