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The decision between long-term and short-term use should be individualized, considering factors such as degree of obesity, presence of complications, treatment response, side effect profile, cost and insurance coverage, and patient preferences and goals

The increase is generally modest and is not considered dangerous for most healthy individuals

Judicial Panel for Multidistrict Litigation (JPML) transferred cases involving harms related to non-arteritic anterior ischemic optic neuropathy (NAION) to a new MDL

In an exploratory analysis, tirzepatide was associated with reduced glucose variability (mean amplitude of glycemic excursion estimated treatment difference 16.5 [95% CI 31.6 to 1.4]

outside those windows, compounding latitude narrows