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Recent studies have shown increasing cases involving gastrointestinal problems linked to glucagon-like peptide-1 (GLP-1) receptor agonists.

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In clinical trials, GLP-1 RAs were shown to significantly lower blood pressure (BP) in addition to HbA1c and body weight (BW), indicating the possibility as anti-hypertensive medication of type 2 DM individuals

[3] Myostatin: a potential therapeutic target for metabolic syndrome

In a phase 2 study, amycretin showed a mean weight reduction of up to 24.3%, which is comparable to or even greater than the weight loss seen with tirzepatide and similar to the results for retatrutide

The drugs have become household names.