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Nauck MA, Meier JJ, Cavender MA, et al

Evidence was critically appraised following the CASP checklist

With time, the success stories eased concerns
Such an absence is not surprising given that this is still a relatively new aesthetic populationbut inevitably means that much of the guidance is derived from expert opinion rather than from study outcomes
You lose visual contact with the injection site, which increases the risk of hitting muscle tissue instead of the subcutaneous layer

Acta Pharmaceutica Sinica
