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Why GLP-1s Might Be the Missing Piece for Menopausal Cognition 5 minute read Summary GLP-1 receptor agonists are emerging as a potential adjunct in managing cognitive symptoms and hot flashes during menopause by improving insulin sensitivity, stabilizing blood glucose, and reducing neuroinflammation

1416 Randomized clinical trials showed that liraglutide, an older generation of GLP-1RAs, reduced whole cortical gray matter, frontal, temporal, and parietal lobe volume compared to placebo in patients with early to moderate AD

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In turn, this can lead to low blood sugar

Formulation decisions are therefore not merely pharmacological details