tirzepatide vs semaglutide trial In the SURMOUNT-5 phase 3b involving adults with obesity without type 2 diabetes, was superior to in reducing body weight and waist circumference. Full trial results and Research Summary: Comparative efficacy and safety of
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Conclusions/interpretation These results suggest that CB1R could be an interesting target for type 1 diabetes while highlighting the regulatory mechanisms of insulitis

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In a crossover trial evaluating semaglutide versus placebo as an add-on to automated insulin delivery therapy in adults with type 1 diabetes, the use of semaglutide was associated with an increased percentage of time spent within the target glucose range, along with reduced insulin requirements.

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