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The most common comorbidity in the Wegovy cohort was depression (21.83% vs
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Inagaki N, Seino Y, Takeda J, Yano H, Yamada Y, Bell GI, et al
Further electrophysiological study showed that, opposite to the effects on arcuate POMC neurons, GLP-1 hyperpolarizes arcuate NPY neurons indirectly via increased GABA A receptor-mediated neurotransmission of local GABAergic interneurons (Secher et al., 2014
doi: 10.1002/jgh3.12780
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