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78 Recent data also show the potential efficacy of GLP-1RAs in renal function in patients without T2D

But one active clinical trial, registered as NCT07092605 on ClinicalTrials.gov, is now specifically studying the effectiveness of microdosed GLP-1 receptor agonists for improving health and quality of life in patients who do not meet traditional prescribing criteria

doi: 10.1126/sciadv.abf1948 [DOI] [PMC free article] [PubMed] [Google Scholar] 10

This article reviews the glucagon-like peptide 1 (GLP-1) agonistbased therapies as a new class of antidiabetic and their potential effects beyond glucose control that may ultimately impact cardiovascular disease

Erratum in: N Engl J Med

It moves the conversation away from willpower alone and towards addressing the underlying biological drivers of hunger and satiety