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Bias implications of outcome misclassification in observational studies evaluating association between treatments and all-cause or cardiovascular mortality using administrative claims

Note that constipation can further delay gastric emptying and worsen nausea

In the 52 weeks that followed, 82.5% regained 25% or more of the weight theyd lost, and the placebo group regained an average of 14% of body weight

This allows the medication to disperse slightly and reduces the chance of it leaking back out through the needle track

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a subgroup analysis by sex was outside the studys scope