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Effect of Liraglutide Therapy on Liver Fat Content in Patients With Inadequately Controlled Type 2 Diabetes: The Lira-NAFLD Study

Taking into account the considerable reduction in incretin effect (i.e., the secretion of insulin in response to oral glucose ingestion mediated by GLP-1 and glucose-dependent insulinotropic peptideGIP) in patients with T2DM and the significant anti-hyperglycemic action, GLP-1 RAs are strongly recommended in the management of patients with T2DM [13]

A recent article revealed that while Ozempic costs $936 a month for Americans, those in the UK pay just $93

And unlike Rybelsus, which has very strict rules around when and how to take it, Orforglipron is expected to have much simpler dosing requirements

23 Clinical trials also indicated that GLP-1 RA treatment for obese patients presented superior weight loss efficacy compared to other anti-obesity medications

[DOI] [PMC free article] [PubMed] [Google Scholar] 178.Yamamoto K, et al
