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Landmark clinical trials, such as the STEP programme for semaglutide published in The New England Journal of Medicine, have demonstrated that these medications can lead to average weight loss of 15% or more when combined with lifestyle changes, a level of efficacy previously achievable only through bariatric surgery
Polyphenols: Colourful berries such as blackcurrants and raspberries, green tea, and dark chocolate are some good options
How long before I can assess whether it is working

Acknowledgements The authors thank to all assistants who participated in the study
