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Interestingly, among these cells, only those with a Th17 polarization state were enriched in patients with MASH-related fibrosis, providing the rationale to target CD4 + T cells with a Th17 polarization state to inhibit MASH-related fibrosis development [73]

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A Cox proportional hazards model was used to test for non-inferiority against the pre-specified risk margin of 1.3 for the hazard ratio (HR) of the composite of CV death, myocardial infarction (MI), or ischemic stroke (MACE) and if non-inferiority was demonstrated, to test for superiority on the two primary endpoints: 1) the composite of hospitalization for heart failure or CV death, and 2) MACE

As he grew older, he became obsessed with chiseling his body into a real-life version of Michelangelos David through dance, bodybuilding, extreme calorie deficits, bingeing and grueling workouts

In a similar randomized controlled trial, Heise et al
