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Writing in Lancet title eClinicalMedicine, the team said they looked at evidence from 48 relevant studies, including 36 randomised controlled trials
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A.et al (2010)
SREBP-2 silencing significantly decreased the expression of HMGCR , SQLE , LXR , CYP7A1 , and PCSK9 genes, while increasing LDLR gene expression compared to nontransfected control cells (Fig
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Ji L, Onishi Y, Ahn CW, et al
However, researchers continue to study the issue, and the boxed warning remains important for people with specific risk factors
