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Gradual Dose Titration Weekly semaglutide injections started low and increased gradually to minimize nausea and digestive side effects while appetite control builds

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Some patients notice appetite changes early

This gastrointestinal response typically peaks during the first 4-6 weeks and decreases significantly as tolerance develops, though proper dose timing and dietary choices play a major role in symptom severity

Forceful water injection can denature the peptide and reduce potency