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Experimental studies in mice have also shown that exenatide can partially reverse age-associated transcriptomic patterns in glial and neurovascular cells [7]

Results for albiglutide were also neutral in the Harmony Outcomes Study, although hospitalization for heart failure was assesed composite with cardiovascular death as a secondary endpoint (67)

Though findings have been promising, there is a need for gold-standard randomized controlled trials to inform clinical decision making and practice

SM is also a consultant for Netdoktor and has served as principal investigator in relation to the development of drugs for the treatment of type 2 diabetes and obesity in collaboration with Novo Nordisk and Bayer, with funds paid to the institution where he is employed, with no personal fee and with no relation to the work reported in this article