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Retatrutide is therefore widely studied in models examining obesity-related metabolic risk factors, including insulin resistance and dysregulated energy balance

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26 In a review of nine cases of EDKA in both T1DM and T2DM patients, four patients in the T1DM subset had recurrent EDKA when restarted on SGLT2i and one patient presented with ketonuria 48 hours after discontinuation of canagliflozin

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