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This study 1) highlights the role of cholesterol in regulating GLP-1R responses in vivo

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There is increasing interest in whether and how GLP-1 medicines impact adipose tissue, muscle, and bone, questions with important clinical implications, especially in individuals who may be frail and experiencing rapid and substantial weight loss

However, the risks of acute myocardial infarction and stroke in the semaglutide group relative to the sitagliptin group were not significant (9.6% vs 9.5%

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