semaglutide pregnancy discontinue 2 months before conception label Study Finds Similar Rates of in Women Who Were and Were Not Prescribed GLP-1 Medications Semaglutide Use During Pregnancy |

Cardiovascular Effects Dose-dependent increases in heart rate were observed with retatrutide: Heart rate increases peaked at approximately 24 weeks Gradually declined thereafter while remaining elevated above baseline This pattern is similar to that observed with other GLP-1 receptor agonists[4] The clinical significance of these heart rate changes requires further evaluation in larger and longer-term studies

But as key patents begin approaching expiry over the coming years, a new phase is unfolding the generics and biosimilar race

This weeks Dear Laura is about GLP-1s, shame, and the fear of being judged for choosing help.

Key implications: Simplified administration may improve patient uptake Broader accessibility across diverse healthcare settings Reinforces the shift toward chronic disease models in obesity care As we move forward, the focus will not only be on efficacy but also on real-world implementation, cost considerations, and long-term outcomes

Safety screening layer (contraindications screen + red flag symptom screen with structured notes fields)

Discover effective home workouts tailored for beginners.