chewing tobacco and kidney disease CDC - Fact Sheet - Smokeless Tobacco: Health Effects What you should know about
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Beyond factors like temperature and taste, the main difference resides in the health affections

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Interestingly, a retrospective cohort study highlighted that cigarette smoking appears to be negatively associated with DIH, which is surprising as induction of CYP2E1 in smokers is expected to increase exposure to toxic metabolites (Zaverucha-do-Valle et al., 2014)

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