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They break down if exposed to heat or digestive enzymes, so they need refrigerated storage and subcutaneous injection
These medications undergo rigorous FDA evaluations, ensuring they provide consistent dosing and proven safety through large-scale clinical trials

Patients should be encouraged to ask questions and report any difficulties or concerns about their injection technique

Unfortunately, the administration of this medication is also complicated involving two periods of mixing separated by a 1530 min wait, depending on the dose (3050mg)

doi: 10.1007/s00125-011-2168-7
