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Multiple long-acting GLP-1RAs reduce rates of major adverse cardiovascular events (MACE) in outcome trials of people with type 2 diabetes [102], heightening interest in understanding the mechanisms linking GLP-1R activation to cardioprotection

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10.1016/S0140-6736(18)32261-X 40 HolmanR

Since estrogen fuels endometriosis lesion activity, this pathway may be relevant for women whose disease is influenced by obesity or estrogen excess

It has gained attention for its potential role in weight management , thanks to its bioactive compounds, including fiber , saponins , flavonoids , and alkaloids