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Description
Once the peristaltic wave reaches the middle of the antrum, the pylorus opens and duodenal contractions are inhibited, allowing small amounts of gastric chyme to be delivered across the pylorus into the duodenum
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15 BuseJBRosenstockJSestiGSchmidtWEMontanyaEBrettJHet al

Substitution for Ala brought in greater than 1000-fold decrease in binding affinity and potency
The mean differences in A1c and body weight between IDegLira and basalbolus therapy and IDeglira and basal glargine were 0.3% and 6.89 kg and 0.65% and 4.04 kg respectively
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