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More than 80 obesity drugs are currently in the pipeline, with a strong emphasis on GLP-1 receptor agonists.

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People taking semaglutide typically reduce their daily calorie intake by 5001,000 calories without strict counting, thanks to decreased appetite and improved satiety signals

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The authors show that GIPR activation enhances entry of GLP-1R agonists into the brain, and this process depends on oligodendrocyte GIPR signaling