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The full analysis set (all patients) for the STEP 1 trial, from the trial product estimand, a modified intention to treat (mITT) population, were used to reflect the efficacy of the target population who stayed on treatment [7]

Its certainly worth a discussion with your current physician to determine if taking levothyroxine at night may help you

Background Several medications reduce antipsychotic weight gain, including metformin, topiramate, and the partial opioid antagonist samidorphan (available as an olanzapine combination pill, Lybalvi)

Testing after your first month ($99 add-on) helps optimize your dose for months 2-6

Or you might hit steady state at the higher dose two weeks later and suddenly experience debilitating nausea that would not have occurred with proper timing

But the company is monitoring how many patients increase to higher doses of the drug, particularly the 9-mg and 25-mg versions