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Semaglutide should not be used concurrently with other GLP-1 receptor agonists or tirzepatide

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Practical Strategies and When to Pause or Adjust Treatment If you experience significant fatigue on GLP-1, evidence-backed strategies include optimizing hydration (fluid losses increase with rapid weight loss), ensuring adequate protein intake (minimum 1.2 g/kg to preserve muscle and energy), and checking biomarkers at 46 weeks to identify correctable deficiencies

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[DOI] [PMC free article] [PubMed] [Google Scholar] 34.Pradhan R., Lu S., Yin H., Yu O.H.Y., Ernst P., Suissa S., Azoulay L

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