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backup contraception is recommended after initiation and dose escalations

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It's important to note that for patients with diabetes and CKD, the ADA and KDIGO now recommend SGLT2 inhibitors for kidney and cardiovascular protection independent of A1C levels, with metformin used when eGFR is adequate (30 mL/min/1.73 m) and tolerated

First, much of the literature is concentrated around metabolic research and sponsor-led clinical development

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According to USP guidelines, a multi-use vial should be discarded 28 days after its initial puncture to maintain product integrity