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There was an increased rate of hypoglycemia in patients treated with JANUVIA

Research indicates that the body's homeostatic mechanisms actively defend against sustained weight loss through increased hunger signaling and reduced satiety hormone production

Dose-Dependent Risk# Across all drugs, GI events and discontinuation rates increase with dose

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The results suggest that addressing excess weight and the underlying metabolic dysfunction associated with PMOS can help restore hormonal balance and improve reproductive function