GLP-1 Drugs & What They Do
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Description
J Clin Endocrinol Metab 103(1):288294
Indian J Med Res (2020) 151:11
doi: 10.1093/asj/sjad364
To increase the stability of GLP-1R, the fusion protein rubredoxin was inserted into intracellular loop 2 (ICL2) of GLP-1R between positions 257 to 262 and 11 mutations were introduced
[DOI] [PubMed] [Google Scholar] 449.Holtmann M.H., Roettger B.F., Pinon D.I., Miller L.J
GLP-1 agonists can reduce plasminogen activator inhibitor (PAI)1 levels, thereby augmenting fibrinolytic potential [96, 97]
