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Retatrutide is contraindicated in patients with MEN-2, medullary thyroid carcinoma, or during pregnancy

Funding for the OASIS-4 clinical trial was provided by Novo Nordisk.

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However, further research is planned to improve our understanding of their effects on obesity-related comorbidities and the underlying mechanism, whether involving direct effects on target tissues or mediated by improvement of adiposity, glucose levels and other CV risk factors

Its safety and effectiveness may differ depending on the standard of the compounding pharmacy

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