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Mechanism: Why these drugs work (and why they cause problems) Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) were initially approved in 2005 for the treatment of type 2 diabetes
The value of microbiome-targeted therapy on lipid indices of patients with type 2 diabetes mellitus: an umbrella meta-analysis of randomized controlled trials
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And GLP-1s do come with side effects that for some patients have been serious enough to lead to discontinuation
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Randomized, double-blind, placebo-controlled trial of orlistat for weight loss in adolescents
