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Unadkat To view or add a comment, sign in GLP-1 Drugs Found to Directly Rewire Brains Reward System Researchers have discovered a neural pathway connecting the amygdala to dopamine neurons that allows these weight-loss medications to reduce the desire for rewarding foods, offering a new explanation for their effectiveness and their impact on addictive behaviors

Fat mass decreases substantially, with visceral fat (the dangerous fat surrounding internal organs) dropping proportionally more than subcutaneous fat

Postprandial Control: Data highlights that sitagliptin significantly reduces 2-hour post-meal glucose spikes, which is a major driver of cardiovascular risk

Meanwhile, GLP-1 receptor activation in the hypothalamus, specifically in the arcuate nucleus and paraventricular nucleus, directly suppresses hunger signals by activating satiety-promoting POMC/CART neurons while inhibiting hunger-promoting NPY/AgRP neurons

Open Here (semaglutide) Tablets 14 mg Once daily Each tablet contains 14 mg semaglutide Oral use only Rx only Dispense the Enclosed Medication Guide to Each Patient 30 tablets 3 blister packs

Elafibranor (GFT505) Elafibranor is an unlicensed dual agonist of PPAR/ receptors, and has been shown to improve steatosis, inflammation, and fibrosis in mouse models of NAFLD [30]