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DPP-4 rapidly degrades incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), which are crucial for regulating glucose homeostasis
Tesamorelin is a GHRH analog that directly signals the pituitary gland to release HGH
Kidney Medicine describes two patients with diabetic kidney disease who rapidly declined after taking GLP-1 drugs
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